ELASTASE, HUMAN NEUTROPHILS
elastase from hog pancreas
CAS: 39445-21-1
Molecular Formula:
ELASTASE, HUMAN NEUTROPHILS - Names and Identifiers
ELASTASE, HUMAN NEUTROPHILS - Physico-chemical Properties
| Water Solubility | Soluble in water. |
| Solubility | H2O: soluble |
| Appearance | lyophilized powder |
| Color | white |
| Storage Condition | -20°C |
| In vivo study | Elastase from porcine pancreas induces emphysema in hamsters. |
ELASTASE, HUMAN NEUTROPHILS - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R42 - May cause sensitization by inhalation |
| Safety Description | S23 - Do not breathe vapour. S24 - Avoid contact with skin. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| RTECS | TS5052000 |
| FLUKA BRAND F CODES | 3-10 |
ELASTASE, HUMAN NEUTROPHILS - Reference
| Reference Show more | 1. LIN, Huapeng, Josen, LIN, et al. Inhibitory effect of iNOS inhibitor on smooth muscle apoptosis of abdominal aortic aneurysm in rats [J]. Advances in modern general surgery in China 2017 03(v.17):16-19. 2. Mao Hui Xiu Chen Mei-Qi Tao Li Jia Tian Yu Ting Lu Ying Lan Liu Jin Hu Liu Wei Juan Li Sun Wenjie Zhang De Wang Shuai Wang gathering Wang Ling. Comparative study on the content of active components and anti-tumor experiment in vitro of wild and cultured scorpion under different elastase activity conditions [J]. Contemporary Chemical engineering 2020 49(02):328-330 334. 3. Cao Guangchao Liu Chunyu Liu Ying, et al. Study on enzymatic extraction process and anti-tumor effect of Chinese herb dung beetle [J]. Chemical Journal 2017 31(002):33-36. 4. Liu Jin Hu Tao Ran Liu Di Zhang Rui Lu Ying Lan Wang Shu Yu Shi Lei Zhao Pan. Optimization of enzymatic hydrolysis conditions of grub powder by dual-enzyme mixed system [J]. West China Journal of Pharmacy, 2019, 34(03):141-144. 5. Lu Yinglan, Liu Ying, Wang Yando, etc. Preliminary Screening of enzymes for enzymatic hydrolysis of earthworm powder [J]. Shandong chemical industry, 2018. 6. Mao huixiu, San xiao, Tube celery, etc. Screening of the best enzyme for eupolyphaga based on semi-Bionic and in vitro anti-tumor cell lines [J]. Shandong chemical industry, 2018, 047(007):10-12. 7. Wang Yando, sangxiao, Fang Yuan, etc. Optimization of enzymatic hydrolysis of Pteris vitrifolia powder by compound enzyme [J]. Food and Drug, 2018, 20(005):367-370. 8. Wang Jing, Gu Zhengwei, Shi Lei, et al. Study on the optimum enzymolysis technology of Tianlong mixed enzyme [J]. Shandong chemical industry, 2018, 047(009):30-32. 9. Wang Ying, Cai meicao, Wang Lina, Liu Chunyu, Wang Jing, Huang Zhiqiang, Zhu Mingzhu, Zhang Youqin, sangxiao, Wang Jihui. Study on the optimum enzyme for enzymatic hydrolysis of Tianlong powder [J]. Central South pharmacy, 2017,15(09):1221-1224. 10. Lu Yinglan, Tian Yuting, Mao huixiu, etc. Optimization of enzymatic hydrolysis of earthworm powder with mixed enzymes by orthogonal experiment [J]. Contemporary Chemical Engineering, 2019, 048(006):1174-1177. 11. Liu Ying, Wang Yando, Cao Guangchao, etc. Preliminary Screening of optimal enzyme for enzymatic hydrolysis of Periplaneta Americana powder [J]. Western Chinese medicine, 2019, 032(009):P.21-24. 12. Liu Chunyu, yetong, Wang Jihui, etc. Preliminary screening of the best enzyme for enzymatic hydrolysis of Pteris vittata powder [J]. Central South Pharmaceutical Sciences, 2017, 015(006):759-762. 13. Fang Yuan, Guo pengchuan, Liu Xiaoyu, etc. Optimization of water extraction process of sea cucumber by ultrasound-enzyme-linked semi-biomimetic method and its antitumor activity in vitro [J]. West China Journal of Pharmacy, 2019, 34(4). 14. Sangxiao, Zhang Rui, Wang Yando, etc. Comparative study on the content of main components and antitumor effect of wild and cultured scorpion after enzymatic hydrolysis [J]. Central South Pharmaceutical Journal, 2018, v.16;No.145(02):171-174. 15. Mao and Y, He Lei, Zhou Yali, etc. Study on preparation technology of ACE inhibitory peptidase from konjac flying powder [J]. Food Industry, 2016(12):127-129, a total of 3 pages. 16. Wang Shiyang, Wang Yando, Cao Guangchao, etc. Preliminary screening of the best enzyme for enzymatic hydrolysis of rhamnosus powder [J]. Contemporary Chemical Engineering, 2018, 47(006): 1111-1154. 17. Wang Ying, Wang Lina, Liu Chunyu, et al. Comparative study on hydrolysis of Tianlong powder by different proteases [J]. Journal of Chemical Engineering, 2017(2). 18. Jiao Fang, Wen-Wang assembly, Zhou Yu, et al. Preliminary Screening of optimal enzyme for enzymatic hydrolysis of Scorpion powder [J]. Shi Zhen Guomai National Medicine 2015v.26;No.242(10):2407-2408. 19. Zhang Panpan, Jia, Wei, Jiao, Fang, Wen, et al. Study on antitumor activity of Scorpion protein [J]. Central South pharmacy 2017(08):1069-1071. 20. Sun Zhiyi, Zhang Ru, Zhao Liping, etc. Comparative study on anti-tumor activity of Scorpion hydrolysate ultrafiltration on three kinds of cells [J]. Shandong chemical industry 2019 48(08):23-24 26. 21. [IF = 4.939] Lili Wen et al."Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic hydrophonic Regions." Mol Pharmaceut. 2018;15(6):2257-2267 22. [IF = 1.65] Hanmei Li et al."Expression of recombinant tachyplesin I in Pichia pastoris."Protein Expres Purif. 2019 May;157:50 23. [IF=4.932] Dandan Zheng et al."Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema."Int Immunopharmacol. 2021 Sep;98:107913 24. [IF=4.821] Qiaozhen Bao et al."Ultrasensitive off-on-off fluorescent nanosensor for protamine and trypsin detection based on inner-filter effect between N,S-CDs and gold nanoparticles."Microchem J. 2021 Sep;168:106409 25. [IF=3.69] Yun-Li Zhao et al."Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice."J Ethnopharmacol. 2020 Sep;259:112949 26. [IF=3.575] Dandan Zheng et al."S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy."Biochem Bioph Res Co. 2021 Jul;562:83 27. [IF=1.813] Wang Ye-fang et al."Ma Xing Shi Gan Decoction Protects against PM2.5-Induced Lung Injury through Suppression of Epithelial-to-Mesenchymal Transition (EMT) and Epithelial Barrier Disruption."Evid-Based Compl Alt. 2020;2020:7176589 28. [IF=4.952] Jie Chen et al."A turn-on fluorescence biosensor for sensitive detection of carbaryl using flavourzyme-stabilized gold nanoclusters."Lwt Food Sci Technol. 2022 Mar;157:113099 |
ELASTASE, HUMAN NEUTROPHILS - Reference Information
| Introduction | elastase is a single peptide chain composed of multiple amino acids, can promote the digestion and decomposition of protein in connective tissue, including the corresponding combination of peptide bonds, water decomposition, etc., but also has obvious protease effect, can be activated against phospholipase, lower cholesterol in the body's blood, but also improve the body's blood lipid serum, which can reduce the density of lipoprotein in the blood, which can increase the body's blood circulation, increase vascular elasticity. Elastase can be used to treat hyperlipidemia, prevent atherosclerosis, fatty liver. It can also be used for tenderness in meat and aquatic processing. |
| biological activity | elastic from porcine pancreas is a single polypeptide chain of 240 amino acid residues. Elastase from porcine pancreas is a serine protease that hydrolyzes proteins and polypeptides. Elastase from porcine pancreas can induce hamster emphysema. |
| in vivo studies | |
| Use | a serine protease that hydrolyzes amino compounds and esters. Elastase is unique in that it acts on elastin. The optimum pH value of the enzyme was 8.5. Soybean trypsin inhibitor and kallikrein inhibitor can inhibit its proteolytic activity, but can not inhibit its elastolytic activity. |
| production method |
Last Update：2024-04-09 20:02:46
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Product Name: elastase from hog pancreas Request for quotationCAS: 39445-21-1
Tel: +86-18721521379
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Mobile: +86-18721521379
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Product Name: EC 3.4.21.36; Pancreatopeptidase E Visit Supplier Webpage Request for quotationCAS: 39445-21-1
Tel: 609-228-6898
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ELASTASE, HUMAN NEUTROPHILS
Phthalhydrazide
3-羟基-3-甲基戊二酸 标准品
Ramelteon Intermediate 1
1-[2-(2-苯乙炔基)苯基]-2,3-丁二烯-1-酮
M-BROMOCINNAMIC ACID
四氨基二氯化钯(II)
Butyric acid, α,β-dioxo-, ethyl ester α-oxiMe (4CI)
Phthalhydrazide
3-羟基-3-甲基戊二酸 标准品
Ramelteon Intermediate 1
1-[2-(2-苯乙炔基)苯基]-2,3-丁二烯-1-酮
M-BROMOCINNAMIC ACID
四氨基二氯化钯(II)
Butyric acid, α,β-dioxo-, ethyl ester α-oxiMe (4CI)